RNA Details
Disease Name
nephritis interstitia
Tissue
kidney
RNA Symbol
mir-21a
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; Masson's trichrome staining
Target
NA
Pathway
PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
"Fuzheng Huayu recipe, a traditional Chinese compound herbal medicine, attenuates renal interstitial fibrosis via targeting the miR-21/PTEN/AKT axis"
Year
2020
Function
miR-21 is the key fibrosis-related miRNA regulated by fuzheng Huayu recipe (FZHY). The ability of fzhy to modulate miR-21/PTEN/Akt signaling may be a viable approach for treating renal interstitial fibrosis (RIF).